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GFR changing with illness and stress

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  • GFR changing with illness and stress

    I had an episode of Acute Renal Failure a year ago which left me with permanent kidney damage. Now I seem to be bouncing back and forth between stage three and stage 4 each time I have a slight infection or experience increased stress. My Creatine and GFR reflect these changes as I go from a GFR of 30 down to a GFR of 23. Has anyone else experienced this. My research seems to indicate that this might be acute renal failure superimposed on CKD.

  • #2
    Hi booksdoc, It is common for an increase in creatinine and lower GFR while sick. Dehydration plays a big part in this along with some meds. I have not heard that stress lowers GFR but it wouldn't surprise me if that were true. Stress really does a number to our bodies and long term stress can cause many problems. My kidney decline was acute with damage also. As you know you won't regain all your function, but you may continue to see some improvements with time. My numbers have slowly gotten better over the last 4 yrs. I hope this will be the case for you also. Do you follow any kind of diet?
    May you always have Love to share, Health to spare, and Friends that care


    Acute Kidney Function Loss 12/07 - GFR 39
    Current GFR 46 - Stage 3 - Controlled HBP

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    • #3
      My ARC episode was just over a year ago and my kidney function has improved from ESRD on dialysis for three months to usually about a GFR of about 30 which is just on the border between stage 3 And 4. Each time I get just a little bit sick which seems to happen every few months my number deteriorate. My renal failure was from toxic shock syndrome; what caused yours if you don't mind sharing? I am trying to stay on a low salt diet with lots of fresh fruits and vegetable and an adequate amount of protein which should be about .6 gm /kg per day. For me that is about 50 gms and is usually more than I can manage. My blood pressure has been a problem because the toxic shock caused an autonomic neuropathy which causes, among other things orthostatic hypotension. In other words, it drops abut 30 points when I go from lying to standing. which causes light headedness and falls if I am not careful.

      When I get ill with anything I totally lose my appetite and even my desire/ability to take in fluids and you're right, I do get dehydrated. I also get very dizzy, the symptoms are much like those I had when I needed dialysis. I am learning not to ignore any illness that lasts more than a day or two as I don't want it to mess with my kidney function. It sounds like you have made a fairly good recovery which does give me hope. Thanks for sharing.

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      • #4
        I'm really glad you have seen improvement but sounds like you are still going through some rough times. I don't know anything about toxic shock syndrome--I will have to look it up. I hope in time the symptoms will ease and you will feel better.

        My kidney function loss was caused by a prep that is commonly used prior to a colonoscopy. "Osmoprep" is the name. At the time, in 2007 there was no warning stated on the prep. Now it comes with the highest black box warning to Drs. For most people this prep is safely taken as prescribed. Now they know that it is dangerous for people who have Ulcerative Colitis or Crohns Disease. The procedure showed that I had UC. I lost 60% function within a couple of weeks. Both kidneys were damaged so now I have CKD. I was one of the lucky ones though as some people required dialysis shortly after using this preparation.

        I wish you the best
        Toni
        May you always have Love to share, Health to spare, and Friends that care


        Acute Kidney Function Loss 12/07 - GFR 39
        Current GFR 46 - Stage 3 - Controlled HBP

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        • #5
          i have recently been very ill my numbers have dropped also. from GFR of 47% to 32%. i am concerned.

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          • #6
            Hello Yumax 224, not to worry too much as I am still functionaing at a GFR sitting at 20 right now, it has gone down by 3 points since April 12. I am a new member to DaVita, and will no doubt be more intune with following guidelines for my stage 4. I had ARF in 2002, ten years ago. I woke up on dialysis after my kidneys crashed. I was on diaylisis for 4 months, and my numbers came down so they tried me off the unit, and here I am years later, doing well p until this past April, when I started experiencing back to back episodes of lupus flare. I am right now in my fourth flare, and on prednisone for relief. Will see my Kidney specialist and Rheumitologist soon. They were never sure if my kidney failure was due to the lupus, which is most likely, or the fact that we were running a fully booked and new B&B, when we were struck with a freak flood, and had 3 feet of dirty water in all of our living area downstairs!, I had walled through the water, to get out of our house. Maybe stress or celebrex had something to do with the failue as well. I do know that it took me almost 5 years to regain me again. Physically and emotionally. It has been a long haul, and thank heavens that I have a great immediate family. My husband and daughter were stoic during all of this upheavl.
            I will be back on the forum after my specialsts visits within the next month or so. Watch your diet, i think this could be the one most significant thing to keep your numbers up and out of range of the dialysis unit. Take good care, and don't be hard on yourself. Take the medications your specialist asks of you. My thoughts are with you.
            Originally posted by yunax224 View Post
            i have recently been very ill my numbers have dropped also. from GFR of 47% to 32%. i am concerned.

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            • #7
              i am either in stage 3 or 4. my creatinine is 3.2. i read several books and "kidney patient,s book by timothy p. ahlstrom" was by far the best. he stayed off dialysis by doing a low protein diet. about 25 gr protein daily and amino acids. but once you are on dialysis you need more protein as the dialysis removes protein from the body. i am not yet on dialysis and will see my neuphrologist next month. he seems to think that i should not worry until i need diaysis and or a kidney transplant. i an trying to learn about a low protein diet with amino acids. aquaman

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